Belgium
Université libre de Bruxelles, Center for Diabetes, Research
- Mariana Igoillo Esteve, PhD - Mechanisms of Monogenic Diabetes, GLP-1 treatment for Wolfram syndrome
- Miriam Cnop MD, PhD - Beta cell dysfunction and Monogenic Diabetes, GLP-1 clinical trial for Wolfram syndrome
KU Leuven
- Catherine Verfaillie, MD - (SCIL) creating models for neurodegenerative disorders to allow study of mechanisms underlying neurodegeneration
- Geert Bultynck, PhD - Calcium signaling in WFS1 knockout cells (LCMS)
- Lieve Moons, PhD - molecular mechanisms underlying neural circuit development, neuroinflammation, neuronal survival and regeneration
- Jan Parys - Laboratory of Cellular and Molecular Signaling (LCMS)
Denmark
University of Copenhagen
- Lisbeth Tranebjærg, MD, PhD - Genetics of Wolfram syndrome
Estonia
University of Tartu, Tartu, Estonia -Institute of Biomedicine and Translational Medicine
- Mario Plaas, PhD - Rodent models of Wolfram syndrome, GLP-1 treatment for Wolfram syndrome
- Eero Vasar, MD, PhD - Molecular mechanisms of Wolfram syndrome
Tartu University Children's Hospital, Tartu, Estonia
- Vallo Tillmann, MD - Diabetes and endocrine issues in Wolfram syndrome, Pediatric endocrinology
Finland
University of Helsinki, Finland
- Mart Saarma, PhD - signaling and biological functions of GDNF family ligands and endoplasmic reticulum located CDNF/MANF neurotrophic factor families
- Maria Lindahl, PhD - Genetics, cell and molecular biology
France
Molecular Mechanisms in Neurodegenerative Diseases, University of Montpellier, EPHE, Montpellier, France
- Benjamin Delprat, PhD - Therapeutic development (gene therapy, drug development), iPSC, rodent and zebrafish models, Molecular mechanisms
INSERM - Institute of Neurosciences of Montpellier
- Cécile Delettre, PhD - ER-mitochondria and Wolfram syndrome, mechanisms of visual impairment, gene therapy, pathophysiology and therapy of inherited optic neuropathies
Université Côte d’Azur, CHU, Inserm, CNRS, IRCAN, France
- Véronique Paquis-Flucklinger,MD, PhD - Genetics of Wolfram syndrome
- Laetitia Aubry, PhD - study of the therapeutic application potentials of iPSCs in Wolfram Syndrome
I-STEM - Evry, France
Germany
Centrum für Reproduktionsmedizin und Andrologie,
WHO Kollaborationszentrum, EAA, Ausbildungszentrum, Universitätsklinikum Münster
WHO Kollaborationszentrum, EAA, Ausbildungszentrum, Universitätsklinikum Münster
- Julia Rohayem, MD, PhD - Pediatric Endocrinology with expertise in Wolfram syndrome, Andrology
Israel
Hadassah Medical Center
- Gil Leibowitz, MD - Senior physician in Endocrinology and Metabolism, Beta-cell ER stress and function
Italy
Università degli Studi di Messina - Messina
- Luciana Rigoli, MD - Departments of Pediatrics, Molecular Biology, Endocrinology
Institute of Neuroscience, CNR, Milan
IRCCS Ospedale San Raffaele, Milan
IRCCS Ospedale San Raffaele, Milan
- Vania Broccoli, PhD - Stem Cells and Neurogenesis Unit, developing novel technologies in stem cells, genetic cell reprogramming and CRISPR/Cas9 gene editing for better modeling and treating of neurological disorders.
Japan
University of Yamaguchi
- Yukio Tanizawa, MD, PhD - Biology of pancreatic Beta Cells, research in GLP-1 receptor signaling, ER stress and beta cell function
Poland
Medical University of Lodz
- Wojciech Mlynarski, MD, PhD - Genetic forms of diabetes, head of Department of pediatric oncology, hematology and diabetology
Spain
Servicio Andaluz de Salud
- Gema Esteban Bueno, MD - Coordinator of multidisciplinary team for Wolfram syndrome
Laboratorio de Genética Molecular, IDIBELL, l’Hospitalet de Llobregat, Barcelona, Spain
- Miguel López de Heredia, PhD - Studies molecular mechanisms and genotype-phenotype correlations in Wolfram syndrome and cystinuria
- Virginia Nunes, PhD - Cancer and human molecular genetics
Universitat Autònoma de Barcelona
- Assumpció Bosch, PhD - professor of the Department of Biochemistry and Molecular Biology, Institute de Neurosciències and the Vall d'Hebron Research Institute.
- Miguel Chillón Rodriguez, PhD - ICREA researcher at the Institute de Neurosciències and the Vall d'Hebron Research Institute.
- Initiating work on gene therapy as a possible treatment for Wolfram syndrome in collaboration with the AFASW.
United Arab Emirates
Al Amal Psychiatry Hospital, Dubai
- Dr. Mehnaz Zafar Ali - Consultant Psychiatrist
- Dr. Wafaa Naji - Senior Resident Psychiatry
- Our team is conducting structured multidisciplinary and longitudinal assessment to understand the behavioral and cognitive symptoms, and address the complexities in treatment of patients with Wolfram syndrome.
United Kingdom
University of Birmingham
- Timothy Barrett, MD, PhD - leading an international randomised controlled trial of repurposed therapy in Wolfram syndrome, performs functional genetic studies and translational research with inherited forms of diabetes
University of Cambridge
- Patrick Yu-Wai-Man - Academic neuro-ophthalmologist with specialist research interest in genetic treatment for mitochondrial eye disorders and WS vision loss
United States
Washington University School of Medicine
- Fumihiko Urano, MD, PhD. - Therapeutic development (regenerative therapy, gene therapy, drug development), iPSC and rodent models, Medical Genetics, Genetic testing, Molecular mechanisms
- Tamara Hershey, PhD. - Neuroimaging of patients with Wolfram syndrome, WU Wolfram Research Clinic
- Bess Marshall, MD - Diabetes and endocrine issues in Wolfram syndrome, Pediatric endocrinology
- Angela Reiersen, MD - Psychiatric Diagnoses in Wolfram syndrome, Child and adolescent psychiatric disorders, Neuropsychiatric Genetics
- Neil White, MD - Diabetes and endocrine issues in Wolfram syndrome, Pediatric endocrinology
NCATS/NIH
- Mark Henderson, PhD - Collaborates with both academic and NIH investigators on projects that aim to identify small molecules that can be used to understand and/or modulate pathogenic events
- Anton Simeonov, PhD - Scientific director at NCATS, novel detection chemistries and techniques
Yale University
- Barbara Ehrlich PhD - Professor of Pharmacology and of Cellular And Molecular Physiology, Study of cell mechanisms for regulation of intracellular calcium concentration
University of Chicago
- Louis Philipson, MD, PhD - endocrinologist and a leading world authority on diabetes mellitus
Columbia University
- Wendy Chung, MD, PhD - Clinical Molecular Genetics and Genomics
- Rudolph Leibel, MD - Clinical Molecular Genetics and Genomics
- Dieter Egli, PhD - study of stem cell derived human beta cells, study of pluripotent stem cells
University of Kansas Medical Center
- Hao Zhu, PhD - CISD2 research
